English Name：Dai Changbo

中文名： 代常波

Phone：+86-532-88701669

Email：daichangbo@caas.cn

Academic Title： Associate Professor

Supervisor：Master Supervisor

Department：Biotechnology Research Center

Group：Tobacco Functional Genomics Innovation Team

Research Area：Genome editing, molecular breeding and plant biotechnology. Research focuses on developing efficient genome editing tools, exploring novel Cas nucleases for precise gene manipulation, and creating elite germplasm with enhanced herbicide resistance and superior agronomic traits, as well as studying the mechanisms and applications of plant tissue culture. 

Publications：

1. Qi Wu, Lixianqiu Wang, Ruiqi Ma, Huan Chen, Meng Chen, Jing Lv, Lei Bo, Changbo Dai, Yuhe Sun, Xinru Wu. NtMBD1 regulates shoot branching regulation and evolutionary differentiation in tobacco (Nicotiana tabacum L.). Plant Science, 2026, 369: 113176. https://doi.org/10.1016/j.plantsci.2026.113176 (Corresponding author).

2. Jing Lv, Xinxi He, Qi Wu, Yuhe Sun, Wenxuan Pu, Changbo Dai.  Research progress and applications of gene activation editing technology in crops. Frontiers in Plant Science, 2026, 17:1787461. https://doi.org/10.3389/fpls.2026.1787461 (Corresponding author).

3. Bingjie Li, Yun Shang, Lixianqiu Wang, Jing Lv, Fengjiao Wang, Jiangtao Chao, Jingjing Mao, Anming Ding, Xinru Wu, Mengmeng Cui, Yuhe Sun, Changbo Dai. Highly efficient multiplex genome editing in dicots using improved CRISPR/Cas systems, Molecular Horticulture, 2025, 5(1):9. https://doi.org/10.1186/s43897-024-00128-w (Corresponding author).

4. Lele Deng, Yekun Yang, Yudong Chen, Xiaodong Xie, Wenwu Yang, Yanju Shuai, Kunmiao Wang, Jianduo Zhang, Haiying Xiang, Meng Li, Zheyan Yu, Changbo Dai, Qi Wu. OEE1 affects the tobacco photosynthesis through the hormone regulation, Industrial Crops and Products, 2025, 231: 121171. https://doi.org/10.1016/j.indcrop.2025.121171 (Corresponding author).

5. Bingjie Li, Chen Chen, Mengmeng Cui, Yuhe Sun, Jing Lv, Changbo Dai. Exploring the potential role of EPSPS mutations for enhanced glyphosate resistance in Nicotiana tabacum, Frontiers in Plant Science, 2025, 16:1516963. https://doi.org/10.3389/fpls.2025.1516963 (Corresponding author).

6. Yan Ao, Qi Wu, Jiqing Zheng, Chi Zhang, Yu Zhao, Rugen Xu, Kaili Xue, Changbo Dai, Miaoyan Yang. Building the physiological barrier: Suberin plasticity in response to environmental stimuli, Plant Science, 2025, 350:112300. https://doi.org/10.1016/j.plantsci.2024.112300 (Corresponding author).

7. Luyao Xue, Fei Xia, Wenting Song, Xinru Wu, Xiaoshan Jin, Qun Zhong, Tingting Sun, Changbo Dai, Guanshan Liu, Yuhe Sun, Chunming Liu, Shengjun Li, Xuefeng Yao, Dawei Wang. A B3 domain transcription factor NtMAB1 regulates the release and outgrowth of axillary buds in Tobacco, Plant Biotechnology Journal, 2025, 23(12): 5492-5509. https://doi.org/10.1111/pbi.70313 (Co-author).

8. Bingjie Li, Anming Ding, Weifeng Wang, Mengmeng Cui, Yuhe Sun, Jing Lv, Changbo Dai. Transcriptomic change in the effects of dichloroquinolinic acid on the development and growth of Nicotiana tabacum. Agronomy, 2024, 14(7), 1364. https://doi.org/10.3390/agronomy14071364 (Corresponding author).

9. Lixianqiu Wang, Bingjie Li, Changbo Dai, Anming Ding, Weifeng Wang, Haoqi Shi, Mengmeng Cui, Yuhe Sun, Jing Lv. Genome-wide identification of MAXs genes for strigolactones synthesis/signaling in solanaceous plants and analysis of their potential functions in tobacco, PeerJ, 2023, 11: e14669. https://doi.org/10.7717/peerj.14669  (Co-author).

10.

Anming Ding, Chuan-Tao Xu, Qiang Xie, Ming-Jin Zhang, Ning Yan, Changbo Dai, Jing Lv, Meng-Meng Cui, Wei-Feng Wang, Yu-He Sun. ERF4 interacts with and antagonizes TCP15 in regulating endoreduplication and cell growth in Arabidopsis, Journal of Integrative Plant Biology, 2022, 64(9): 16

3-1689. https://doi.org/10.1111/jipb.13323 (Co-author).

11. Jing Lv, Changbo Dai, Weifeng Wang, Yuhe Sun. Genome-wide identification of the tobacco GDSL family and apical meristem-specific expression conferred by the GDSL promoter. BMC Plant Biology, 2021, 21(1): 501. https://doi.org/10.1186/s12870-021-03278-x (Corresponding author).

12. Jing Lv, Ya-Qiong Chen, An-Ming Ding, Bo Lei, Jing Yu, Xiao-Ming Gao, Changbo Dai, Yu-He Sun. Control of axillary bud growth in tobacco through toxin gene expression system, Scientific Reports, 201, 11(1): 17513. https://doi.org/10.1038/s41598-021-96976-3 (Corresponding author).

13. Jing Lv, Chang-Bo Dai, Yu-He Sun. Induction of male sterility in tobacco by anther-specific expression of the gene for ricin enzymatic subunit A chain RTA, Molecular Biotechnology, 2020, 62

8):364-369. https://doi.org/10.1007/s12033-020-00252-0 (Co-author).

14. Xinru Wu, Daping Gong, Fei Xia, Changbo Dai, Xingwei Zhang, Xiaoming Gao, Shaomei Wang, Xu Qu, Yuhe Sun, Guanshan Liu. A two-step mutation process in the double WS1 homologs drives the evolution of burley tobacco, a special chlorophyll-deficient mutant with abnormal chloroplast development, Planta, 2020, 251(1): 10. https://doi.org/10.1007/s00425-019-03312-1 (Co-author).

15. Yun Shang, Changbo Dai, Myeong Min Lee, June M Kwak, Kyoung Hee Nam. BRI1-Associated Receptor Kinase 1 Regulates Guard Cell ABA Signaling Mediated by Open Stomata 1 in Arabidopsis, Molecular Plant, 2016, 9(3): 447-460. https://doi.org/10.1016/j.molp.2015.12.014 (Co-author).

16. Changbo Dai, Likun Liu, Myeong Hyeon Wang. Characterization of a Methionine Sulfoxide Reductase B from Tomato (Solanum lycopersicum), and Its Protecting Role in Saccharomyces cerevisiae, Protein Journal, 2013, 32, 39–47. https://doi.org/10.1007/s10930-012-9457-y (First author).

17. Changbo Dai, Woong Han, Myeong-Hyeon Wang. Two highly homologous methionine sulfoxide reductase A from tomato (Solanum lycopersicum), exhibit distinct catalytic properties, Protein Journal, 2012, 31(4): 285-292. https://doi.org/10.1007/s10930-012-9403-z (First author).

18. Changbo Dai and Myeong Hyeon Wang. Characterization and functional analysis of methionine sulfoxide reductase A gene family in tomato, Molecular Biology Reports, 2012, 39: 6297-6308. https://doi.org/10.1007/s11033-012-1451-0 (First author).

19. Changbo Dai and Myeong-Hyeon Wang. Isolation and characterization of thioredoxin and NADPH-dependent thioredoxin reductase from tomato (Solanum lycopersicum), BMB Reports, 2011, 44(10): 692-697. https://doi.org/10.5483/bmbrep.2011.44.10.692 (First author).

20. Changbo Dai, Naresh Kumar Singh, Myungho Park. Characterization of a novel methionine sulfoxide reductase A from tomato (Solanum lycopersicum), and its protecting role in Escherichia coli, BMB Reports, 2011, 44(12):805-810. https://doi.org/10.5483/bmbrep.2011.44.12.805 (First author).